The ASUS ROG Zenith Extreme Alpha X399 is an AMD X399 (TR4) EATX gaming motherboard designed for AMD Ryzen Threadripper processors. It features an 8+8 phase power delivery system with premium alloy chokes and capacitors for extreme overclocking capability, supporting Quad Channel DDR4 memory with DOCP profiles up to 3600MHz across 8 DIMM slots. The board provides 4x PCIe 3.0 x16 slots (x16/x16/x16/x8) with reinforced SafeSlots, plus triple M.2 slots (two with ROG DIMM.2 extension card) and U.2 port for high-speed storage expansion. Networking includes Aquantia 10G LAN, Intel Gigabit Ethernet, and 802.11ad WiFi with MU-MIMO support. The motherboard features comprehensive cooling solutions with multiple fan headers, water cooling zones, and an M.2 heatsink. RGB lighting is controlled via Aura Sync with multiple headers, including an addressable Gen 2 header. Additional features include USB 3.1 Gen 2 Type-C (front and rear), BIOS FlashBack button, SupremeFX S1220 audio with ESS Sabre DAC, and pre-mounted I/O shield. The board also includes ROG GameFirst IV for network optimization, ROG RAMCache for performance boosting, and supports ASUS 5-Way Optimization for automated system tuning.